Variable Omicron of Concern (VOC) – data as of December 15, 2021 (12:00)

According to information from public sources, confirmed cases have been reported by 27 EU/EEA countries: Austria (59), Belgium (90), Croatia (3), Cyprus (3), Czechia (9), Denmark ( 310*), Estonia (6**), Finland (20), France (170), Germany (102), Greece (5), Hungary (2), Iceland (20), Ireland (18), Italy (27) Latvia (14), Liechtenstein (1), Lithuania (2), Luxembourg (1), Netherlands (80), Norway (1) *** 498), Portugal (69), Romania (11), Slovakia (3), Slovenia (4), Spain (51), Sweden (51). Two new countries (Lithuania and Slovenia) have reported cases since yesterday, and several countries have reported a number of possible cases.

Although initially reported cases were related to travel, an increasing number of cases are now being reported as acquired within the EU/EEA, including as part of clusters and outbreaks, with cases also being detected in surveillance systems representation.

Preliminary analysis of primary Omicron VOC cases reported to TESSy shows that imported or travel-related cases account for 13% (22), while 70% (121) of cases reported to TESSy were locally acquired. , including 45% (78) cases sampled as part of local investigations into the outbreak.

EU/EEA countries that have reported cases unrelated to epidemiological travel include Belgium, Denmark, Finland, Hungary, Norway, the Netherlands, Portugal, Spain, Sweden and Iceland. This indicates that undetected community transmission could be ongoing in the EU/EEA.

All cases in the EU/EEA for which information on severity is available were either asymptomatic or mild. Within the EU/EEA, no Omicron-related deaths have been reported to date. However, these data should be evaluated with caution, as the number of confirmed cases is too low to understand whether the clinical spectrum of Omicron disease differs from previously detected variants.

Countries and territories outside the EU/EEA have reported 7,521 confirmed cases. The 53 countries and regions that have reported confirmed cases are: Argentina, Australia, Bahrain, Bangladesh, Bermuda (UK), Botswana, Brazil, Cambodia, Canada, Chile, China, Cuba, Fiji, Ghana, Gibraltar (UK), India, Israel, Japan, Jordan, Kuwait, Lebanon, Malawi, Malaysia, Maldives, Mauritius, Mexico, Namibia, Nepal, Nigeria, Oman, Pakistan, Philippines, Russia, Rwanda, Saudi Arabia, Senegal, Sierra Leone, Singapore, South Africa, South Korea, Sri Lanka, Switzerland, Taiwan, Thailand, Trinidad and Tobago, Tunisia, Turkey, Uganda, UAE, UK, USA, Zambia and Zimbabwe.

On December 13, 2021, the UK’s Health Security Agency reported one death linked to Omicron. This person was diagnosed at the hospital.

In general, there were 10 150 confirmed cases globally, reported by 80 countries.

A summary of available studies on the antibody capacity of convalescent or post-vaccination serum against Omicron VOC is available in the Epidemiological Update as of December 10, 2021.

The results of a vaccine efficacy study conducted in the United Kingdom have been published as a preprint (not yet reviewed). The study shows a reduced efficacy of the vaccine against Omicron VOC infection compared to Delta VOC infection in individuals who received two doses of the vaccine. However, the efficacy of the vaccine against omicron infection was similar to that of delta infection in individuals who received an additional dose. The study did not assess the effectiveness of the vaccine against severe outcomes.

Table 1. Confirmed Omicron VOC cases of SARS-CoV-2 reported by public sources, as of December 15, 2021 (12:00)



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